product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-Nesprin 3
catalog :
MBS375081
quantity :
0.1 mL
price :
415 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
product information
catalog number :
MBS375081
products type :
Antibody
products full name :
Rabbit Anti-Nesprin 3
products short name :
Nesprin 3
products name syn :
C14orf49 antibody; chromosome 14 open reading frame 49 antibody; FLJ25605 antibody; MGC75267 antibody; Nesprin 3 antibody; Nesprin-3 antibody; NET53 antibody; SYNE3 antibody; SYNE3_HUMAN antibody
other names :
nesprin-3; Nesprin-3; nesprin-3; nuclear envelope spectrin repeat protein 3; spectrin repeat containing, nuclear envelope family member 3; Nuclear envelope spectrin repeat protein 3
other gene names :
SYNE3; SYNE3; NET53; Nesp3; C14orf49; C14orf49
uniprot entry name :
SYNE3_HUMAN
host :
Rabbit
reactivity :
Mouse
sequence length :
975
form :
Serum
tested application :
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluoresence (IF)
app notes :
Optimal antibody dilution should be determined by titration, however as a guideline try between 1:500-1:2000
other info1 :
Target Antigen: Nesprin 3. Immunogen: GST-Nesprin 3 peptide
ncbi gi num :
145580592
ncbi acc num :
NP_689805.3
ncbi gb acc num :
NM_152592.3
uniprot acc num :
Q6ZMZ3
ncbi mol weight :
68,582 Da
uniprot summary :
SYNE3: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow- induced centrosome polarization and directional migration in aortic endothelial cells. Belongs to the nesprin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 14q32.13. Cellular Component: nuclear outer membrane; rough endoplasmic reticulum; membrane; integral to membrane; nuclear envelope. Molecular Function: actin filament binding; protein binding. Biological Process: regulation of cell shape; cytoskeleton organization and biogenesis
size1 :
0.1 mL
price1 :
415 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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