catalog number :
MBS375063
products full name :
Mouse Anti-Receptor Tyrosine Phosphatase Beta (phosphacan) [122.2]
products short name :
Receptor Tyrosine Phosphatase Beta
products name syn :
PTPRB antibody; HPTP BETA antibody; HPTPB antibody; Phosphacan receptor typeB antibody; Protein tyrosine phosphatase receptor type B antibody; PTPB antibody; PTPRB antibody; R PTP BETAantibody; RPTPB antibody
other names :
receptor-type tyrosine-protein phosphatase zeta isoform 3; Receptor-type tyrosine-protein phosphatase zeta; receptor-type tyrosine-protein phosphatase zeta; protein tyrosine phosphatase, receptor-type, zeta polypeptide 1; protein-tyrosine phosphatase receptor type Z polypeptide 2; receptor-type tyrosine phosphatase beta/zeta; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2
other gene names :
PTPRZ1; PTPRZ1; PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2; HTPZP2; PTPRZ; PTPRZ2; PTPZ; R-PTP-zeta
uniprot entry name :
PTPRZ_HUMAN
reactivity :
Receptor Tyrosine Phosphatase Beta (phosphacan) ;
form :
Antibody grown in protein free medium, then concentrated and dialysed against PBS;
tested application :
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Optimal antibody dilution should be determined by titration, however as a guideline try between 1:1000-1:2500
other info1 :
Target Antigen: Receptor Tyrosine Phosphatase Beta (phosphacan). Immunogen: Embryonic rat brain proteoglycans
other info2 :
Myeloma/fusion Partners: P3X. Research Areas: Cell Biology; signal transduction
ncbi acc num :
NP_001193768.1
ncbi gb acc num :
NM_001206839.1
ncbi mol weight :
162,663 Da
ncbi pathways :
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (515); Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
uniprot summary :
PTPRZ1: May be involved in the regulation of specific developmental processes in the CNS. Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor protein phosphatase, tyrosine; Motility/polarity/chemotaxis; EC 3.1.3.48; Membrane protein, integral. Chromosomal Location of Human Ortholog: 7q31.3. Cellular Component: proteinaceous extracellular matrix; integral to plasma membrane. Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity. Biological Process: central nervous system development; learning and/or memory; axonogenesis; oligodendrocyte differentiation; hemopoietic progenitor cell differentiation; protein amino acid dephosphorylation. Disease: Helicobacter Pylori Infection, Susceptibility To