catalog number :
MBS373037
products full name :
Prolactin
products short name :
Prolactin
other names :
prolactin; Prolactin; prolactin; OTTHUMP00000017727; prolactin
other gene names :
PRL; PRL; PRL
uniprot entry name :
PRL_HUMAN
form :
Prolactin is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Normal Pituitary. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Prolactin is a peptide hormone primarily associated with lactation. It is synthesized and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). It is also produced in other tissues including the breast and the decidua. Pituitary prolactin secretion is regulated by neuroendocrine neurons in the hypothalamus, most importantly by neurosecretory dopamine neurons of the arcuate nucleus, which inhibit prolactin secretion. Prolactin is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with lactotrope cells.
ncbi acc num :
NP_000939.1
ncbi gb acc num :
NM_000948.3
ncbi mol weight :
25745 Da
ncbi pathways :
Amyloids Pathway 366238!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!ErbB4 Signaling Events Pathway 137991!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Prostaglandin Synthesis And Regulation Pathway 198912
uniprot summary :
Function: Prolactin acts primarily on the mammary gland by promoting lactation. Subcellular location: Secreted. Sequence similarities: Belongs to the somatotropin/prolactin family. Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.