catalog number :
MBS373035
products full name :
Myoglobin
products short name :
Myoglobin
other names :
myoglobin; Myoglobin; myoglobin; OTTHUMP00000197919; OTTHUMP00000197921; OTTHUMP00000197922; OTTHUMP00000197935; myoglobin; N/A
other gene names :
MB; MB; PVALB; MGC13548; N/A
uniprot entry name :
MYG_HUMAN
form :
Myoglobin is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Skeletal Muscle. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Myoglobin is a single-chain globular protein of 153 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. With a molecular weight of 16.7 kDa, it is the primary oxygen-carrying pigment of muscle tissues. Immunostaining with Myoglobin provides a specific, sensitive and practical procedure for the identification of Rhabdomyosarcoma. Since myoglobin is found exclusively in skeletal and cardiac muscle and is not present in any other cells of the human body, it may be used to distinguish Rhabdomyosarcoma from other soft-tissue tumors. Myoglobin staining is also useful when demonstrating rhabdomyoblastic differentiation in other tumors, e.g., Neurogenic Sarcomas and Malignant Mixed Mesodermal Tumors of the uterus and ovary.
ncbi acc num :
NP_976312.1
ncbi gb acc num :
NM_203378.1
ncbi mol weight :
17053 Da
ncbi summary :
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
uniprot summary :
Function: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Sequence similarities: Belongs to the globin family.