catalog number :
MBS373013
products short name :
FSH
other names :
FSH; Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein
other gene names :
BRD2; KIAA9001; RING3
uniprot entry name :
BRD2_HUMAN
form :
FSH is a purified immunoglobulin fraction of rabbit antiserum that is filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Normal Pituitary. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotropes in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease. It reacts with FSH-producing cells.
ncbi mol weight :
88,061 Da
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
uniprot summary :
Function: May play a role in spermatogenesis or folliculogenesis. Subunit structure: Homodimer. Interacts with E2F1 and with histone H4 acetylated at 'Lys-13'. Ref.15. Subcellular location: Nucleus. Domain: One bromodomain is sufficient for a partial interaction with histone H4 acetylated at 'Lys-13'. Sequence similarities: Contains 2 bromo domains.Contains 1 ET domain. Sequence caution: The sequence AAA68890.1 differs from that shown. Reason: Erroneous initiation.