product summary
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company name :
MyBioSource
product type :
antibody
product name :
Factor VIII-Related Antigen
catalog :
MBS373010
quantity :
5 + Control Slides
price :
115 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
polyclonal
more info or order :
product information
catalog number :
MBS373010
products type :
Antibody
products full name :
Factor VIII-Related Antigen
products short name :
Factor VIII-Related Antigen
other names :
factor VIII
other gene names :
FVIII
clonality :
Polyclonal
isotype :
IgG
clone :
polyclonal
host :
Rabbit
reactivity :
Human, Dog, Cat
form :
Factor VIII antibody is a purified immunoglobulin fraction of rabbit antiserum, diluted in phosphate buffered saline, pH 7.6, with protein, and preserved with sodium azide.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Skin, Placenta. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Factor VIII (F VIII) is an essential clotting factor. The lack of normal F VIII causes Hemophilia A, an inherited bleeding disorder. FVIII is a glycoprotein procofactor synthesized and released into the bloodstream by the liver. In the circulating blood, it is mainly bound to von Willebrand factor (vWF, also known as Factor VIII-related antigen) to form a stable complex. Upon activation by thrombin or Factor Xa, it dissociates from the complex to interact with Factor IXa, the coagulation cascade. It is a cofactor to Factor IXa in the activation of Factor X, which, in turn, with its cofactor Factor Va, activates more thrombin. Thrombin cleaves fibrinogen into fibrin which polymerizes and crosslinks (using Factor XIII) into a blood clot. This antibody reacts with endothelial cells in normal, reactive, and neoplastic blood cells. F VIII antibody has helped to establish the endothelial nature of some lesions of disputed histogenesis, e.g., Kaposi`s Sarcoma and Cardiac Myxoma. Not all endothelial cells synthesize (or store) this molecule; therefore, it should not be surprising that not all tumors of endothelial differentiation (benign or malignant) react with this antigen.
ncbi gi num :
4262857
ncbi acc num :
AAD15005.1
ncbi gb acc num :
S81579.1
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
size1 :
5 + Control Slides
price1 :
115 USD
size2 :
3 ml (Prediluted)
price2 :
130
size3 :
0.1 mL (Concentrate)
price3 :
155
size4 :
7 ml (Prediluted)
price4 :
165
size5 :
0.5 mL (Concentrate)
price5 :
180
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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