product summary
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company name :
MyBioSource
product type :
antibody
product name :
TIA-1
catalog :
MBS370145
quantity :
5 + Control Slides
price :
115 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TIA-1
more info or order :
product information
catalog number :
MBS370145
products type :
Antibody
products full name :
TIA-1
products short name :
TIA-1
products gene name :
TIA-1
clonality :
Monoclonal
isotype :
IgG1
clone :
TIA-1
host :
Mouse
reactivity :
Human
form :
TIA-1 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Tonsil, Spleen, Anaplastic Large Cell Lymphoma. Localization: Cytoplasmic (Granular)
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
TIA-1 (T-cell intracytoplasmic antigen) is a 15 kDa cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. The expression of TIA-1 has been studied in Anaplastic Large Cell Lymphomas (ALCL), NK-cell Lymphomas, Peripheral T-cell Lymphomas, T-cell Lymphocytosis, B-cell Lymphomas and Lymphoblastic Leukemia, Hodgkin's, etc. Studies show that 60 to 70% of Anaplastic Large Cell Lymphomas react with TIA-1. TIA-1 reacts with most Large Granular Lymphocytic Leukemias, Hepatosplenic T-cell Lymphomas, intestinal T-cell Lymphomas, NK-like T-cell Lymphomas, NK-cell Lymphomas, nasal T/NK-cell Lymphomas, subcutaneous T-cell Lymphomas and Pulmonary Angiocentric Lymphomas of T- or NK-phenotype. All B-cell Lymphomas, Hodgkin's and Lymphoblastic Leukemias are negative for TIA-1.
size1 :
5 + Control Slides
price1 :
115 USD
size2 :
3 ml (Prediluted)
price2 :
155
size3 :
0.1 mL (Concentrate)
price3 :
205
size4 :
7 ml (Prediluted)
price4 :
220
size5 :
15 ml (Prediluted)
price5 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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