product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
CD2
catalog :
MBS370122
quantity :
3 ml
price :
290 USD
clonality :
monoclonal
host :
mouse
reactivity :
Rhesus monkey
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS370122
products type :
Antibody
products full name :
CD2
products short name :
CD2
other names :
CD2 molecule; CD2 molecule; cluster of differentiation 2; N/A
products gene name :
CD2
other gene names :
CD2; N/A
clonality :
Monoclonal
isotype :
IgG1/K
clone :
AB75
host :
Mouse
form :
CD2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Tonsil. Localization: Membranous
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
CD2 is a cell-adhesion molecule found on the surface of T-cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. Due to its structural characteristics, CD2 is a member of the immunoglobulin superfamily; it possesses two immunoglobulin-like domains in its extracellular portion. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T-cells. It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B-lymphocytes. CD2 is implicated in the triggering of T-cells; the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of Lymphomas and Leukemias of T-cell origin. As with other pan-T cell antigens, CD2 may be aberrantly deleted in some neoplastic T-cell populations, especially Peripheral T-cell Lymphomas.
ncbi gi num :
306518584
ncbi acc num :
NP_001182402.1
ncbi gb acc num :
NM_001195473.1
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway 86739!!Cell Adhesion Molecules (CAMs) Pathway 480!!Hematopoietic Cell Lineage Pathway 86748!!Hematopoietic Cell Lineage Pathway 489
size :
3 ml
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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