catalog number :
MBS370111
products full name :
Tryptase
products short name :
Tryptase
other names :
tryptase; Tryptase; tryptase
other gene names :
MCT7; MCT7; PMCT7; TPSB1
uniprot entry name :
TRYT_PIG
form :
Tryptase is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated,
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Mast Cell Containing Tissues. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Tryptase is the most abundant secretory granule-derived serine proteinase contained in mast cells and has recently been used as a marker for mast cell activation. It is involved in allergenic response and is suspected to act as a mitogen for fibroblast lines. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis. Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase.Human mast cell tryptase is considered to be an important marker of mast cell activation as well as an important mediator of inflammation. Anti-tryptase is a good marker for mast cells, basophils, and their derivatives.
ncbi acc num :
NP_999356.1
ncbi gb acc num :
NM_214191.1
ncbi mol weight :
27378 Da
uniprot summary :
Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Catalytic activity: Preferential cleavage: Arg- -Xaa, Lys- -Xaa, but with more restricted specificity than trypsin. Subunit structure: Homotetramer. Subcellular location: Secreted. Note: Released from the secretory granules upon mast cell activation. Sequence similarities: Belongs to the peptidase S1 family. Tryptase subfamily.Contains 1 peptidase S1 domain.
size1 :
5 + Control Slides
size2 :
3 ml (Prediluted)
size3 :
0.1 mL (Concentrate)
size4 :
7 ml (Prediluted)
size5 :
0.5 mL (Concentrate)