product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Myogenin
catalog :
MBS370091
quantity :
3 ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
F5D
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS370091
products type :
Antibody
products full name :
Myogenin
products short name :
Myogenin
other names :
myogenin; Myogenin; myogenin; myf-4; myogenic factor 4; OTTHUMP00000039094; Myogenic factor-4; myogenin; class C basic helix-loop-helix protein 3; myogenin (myogenic factor 4); Class C basic helix-loop-helix protein 3; bHLHc3; Myogenic factor 4
other gene names :
MYOG; MYOG; MYF4; bHLHc3; MYOGENIN; BHLHC3; MYF4
uniprot entry name :
MYOG_HUMAN
clonality :
Monoclonal
isotype :
IgG1/K
clone :
F5D
host :
Mouse
form :
Myogenin is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated,dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Rhabdomyosarcoma. Localization: Nuclear
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Myogenin is a transcription factor active in muscles. In particular, it is a myogenic regulatory factor. Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin is restricted to cells of skeletal-muscle origin. It is, therefore, a useful marker for tumors of the muscle lineage, being strongly expressed in Alveolar Rhabdomyosarcomas. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of Rhabdomyosarcoma and some Leiomyosarcomas. Positive nuclear staining may occur in Wilm's Tumor.
ncbi gi num :
18765727
ncbi acc num :
NP_002470.2
ncbi gb acc num :
NM_002479.4
uniprot acc num :
P15173
ncbi mol weight :
24906 Da
ncbi pathways :
CDO In Myogenesis Pathway 160998!!Hypertrophy Model Pathway 198828!!Id Signaling Pathway 198871!!Myogenesis Pathway 160997!!Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway 169352
ncbi summary :
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq]
uniprot summary :
Function: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. Subunit structure: Efficient DNA binding requires dimerization with another bHLH protein. Subcellular location: Nucleus. Sequence similarities: Contains 1 basic helix-loop-helix (bHLH) domain.
size :
3 ml
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!