catalog number :
MBS370088
products full name :
Melanosome HMB45
products short name :
Melanosome HMB45
form :
HMB-45 Melanoma antibody is a mouse monoclonal from tissue culture supernatant diluted in PhosphateBuffered Saline, pH 7.6, with protein base, and preserved with Sodium Azide preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Melanoma. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
HMB-45 is a mouse monoclonal antibody that reacts against an antigen present in melanocytic tumors such as Melanomas. The antibody was generated to an extract of Melanoma. It reacted positively against Melanocytic Tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, this antibody reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. This antibody is very useful to identify Malignant Melanoma. Metastatic Amelanotic Melanoma can often be confused with a variety of poorly differentiated Carcinomas, Large Cell Lymphomas, Sarcomas, Spindle Cell Carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immunoreacts with antibody to S-100 protein and with this melanoma antibody, is, with rare exception, a Melanoma.
size1 :
5 + Control Slides
size2 :
3 ml (Prediluted)
size3 :
0.1 mL (Concentrate)
size4 :
7 ml (Prediluted)
size5 :
0.5 mL (Concentrate)