catalog number :
MBS370083
products full name :
Ki-67 RMab
products short name :
Ki-67
products name syn :
Ki-67 RMab
other names :
Ki-67; Ki-67 protein
products gene name :
Ki-67
other gene names :
Mki67; Ki-67
uniprot entry name :
Q61769_MOUSE
form :
Ki-67 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Breast Carcinoma, Astrocytoma, Colon Carcinoma. Localization: Nuclear
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
The Ki-67 protein is a cellular marker for proliferation. It is strictly associated with cell proliferation. During the interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). Ki-67 is an excellent marker to determine the growth fraction of a given cell population. The fraction of Ki-67-positive tumor cells (the Ki-67 labeling index) is often correlated with the clinical course of cancer. The best-studied examples in this context are Carcinomas of the Prostate and the Breast.
ncbi mol weight :
324,429 Da
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149