catalog number :
MBS370057
products full name :
Cytokeratin Cocktail, AE1 & AE3
products short name :
Cytokeratin Cocktail, AE1 & AE3
reactivity :
Human, Dog, Cat, Mouse, Rat, Monkey, Rabbit, Chicken, Horse
form :
Cytokeratin AE1/AE3 is cocktail of a mouse monoclonal antibodies derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2-8 Degree C. Do not use after expiration date listed on package label. Temperature fluctuations should be avoided. Store appropriately when not in use, and avoid prolonged exposure to room temperature conditions
other info1 :
Control: Prostate, Skin, Colon, Stomach, Salivary Gland. Localization: Cytoplasmic. Immunogen: Purified human epidermal keratin
other info2 :
Reactivity Note: Paraffin, Frozen. Intended Use: This antibody is intended for use in Immunohistochemical applications on formalin- fixed paraffin-embedded tissues (FFPE), frozen tissue sections and cell preparations. Interpretation of results should be performed by a qualified medical professional
products description :
Cytokeratins are intermediate-filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of cytokeratins: the low-weight, acidic Type I cytokeratins and the high-weight, basic or neutral Type II cytokeratins. Cytokeratins are usually found in pairs comprising a Type I cytokeratin and a Type II cytokeratin. Expression of these cytokeratins is frequently organ or tissue-specific. Cytokeratin cocktail AE1/AE3 is well suited to distinguish Epithelial Carcinoma from Non-epithelial malignan-cies and is used to aid Epithelial Tumor classification. This antibody has been used to characterize the source of various neoplasms and to study the distribution of keratin-containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues. This antibody has shown high sensitivity and specificity in recogniz-ing epithelial cells of neoplastic origin.
size1 :
5 + Control Slides
size2 :
3 ml (Prediluted)
size3 :
7 ml (Prediluted)
size4 :
0.1 mL (Concentrate)
size5 :
0.5 mL (Concentrate)