catalog number :
MBS370048
products full name :
COX-2 RMab
products short name :
COX-2
products name syn :
COX-2 RMab
products gene name :
COX-2
reactivity :
Human, Dog, Cat, Mouse, Rat
form :
COX-2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Adenocarcinoma of Colon. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, Cyclooxygenase (COX) is an enzyme that is responsible for formation of important biological mediators called prostanoids (including prostaglandins, prostacyclin and thromboxane). Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain; this is the method of action of well-known drugs such as aspirin and ibuprofen. COX-2 inhibition by nonsteroidal anti-inflammatory agents has been shown to decrease angiogenesis and tumor growth, and promote apoptosis. COX-2 overexpression has been associated with increased microvascular density, and VEGF protein expression in head and neck Squamous-cell Carcinomas and is a poor prognostic indicator in this entity as well. COX-2 overexpression has also been suggested as a poor prognostic indicator in Carcinomas of the colon, breast, pancreas, and Adenocarcinomas of the lung.
size1 :
5 + Control Slides
size2 :
3 ml (Prediluted)
size3 :
0.1 mL (Concentrate)
size4 :
7 ml (Prediluted)
size5 :
15 ml (Prediluted)