product summary
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company name :
MyBioSource
product type :
antibody
product name :
Chromogranin A
catalog :
MBS370046
quantity :
5 + Control Slides
price :
115 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LK2H10
reactivity :
human, mouse, dog
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS370046
products type :
Antibody
products full name :
Chromogranin A
products short name :
Chromogranin A
other names :
chromogranin-A; Chromogranin-A; chromogranin-A; cgA; chromogranin A
other gene names :
Chga; Chga; Chga
uniprot entry name :
CMGA_MOUSE
clonality :
Monoclonal
isotype :
IgG1/K
clone :
LK2H10
host :
Mouse
reactivity :
Human, Dog, Cat
form :
Chromogranin A is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Pancreas. Localization: Cytoplasmic
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory pro-teins. Examples of cells producing chromogranin A are the adrenal medulla, enterochromaffin-like cells and beta cells of the pancreas. The function of chromogranin A is unknown but it is a precursor to 3 functional peptides: vasostatin, pancreastatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A is an excellent marker for Carcinoid Tumors, Pheochromocytomas, Paragangliomas, and other Neuroendocrine Tumors. Coexpression of chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms. It has been identified in a wide variety of endocrine tissues including the pituitary, pancreas, hypothalamus, thymus, thyroid, intestine and parathyroid. It is generally accepted that the coexpression of certain keratins and chromogranin means neuroendocrine lineage. The presence of strong chromogranin staining and absence of keratin staining should raise the possibility of paraganglioma. Most pituitary adenomas and prolactinomas readily express chromogranin.
ncbi gi num :
6680932
ncbi acc num :
NP_031719.1
ncbi gb acc num :
NM_007693.1
uniprot acc num :
P26339
ncbi mol weight :
49943 Da
uniprot summary :
Function: Pancreastatin strongly inhibits glucose induced insulin release from the pancreas. Subcellular location: Secreted. Note: Neuroendocrine and endocrine secretory granules. Post-translational modification: CgA is O-glycosylated. Miscellaneous: Binds calcium with a low-affinity. Sequence similarities: Belongs to the chromogranin/secretogranin protein family.
size1 :
5 + Control Slides
price1 :
115 USD
size2 :
3 ml (Prediluted)
price2 :
135
size3 :
7 ml (Prediluted)
price3 :
150
size4 :
0.1 mL (Concentrate)
price4 :
165
size5 :
15 ml (Prediluted)
price5 :
215
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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