product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD30
catalog :
MBS370025
quantity :
3 ml
price :
200 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ber-H2
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS370025
products type :
Antibody
products full name :
CD30
products short name :
CD30
other names :
CD30 antigen; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; OTTHUMP00000001783; OTTHUMP00000221481; cytokine receptor CD30; lymphocyte activation antigen CD30; tumor necrosis factor receptor superfamily, member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30
products gene name :
CD30
other gene names :
TNFRSF8; TNFRSF8; CD30; Ki-1; D1S166E; CD30; D1S166E
uniprot entry name :
TNR8_HUMAN
clonality :
Monoclonal
isotype :
IgG1/K
clone :
Ber-H2
host :
Mouse
form :
CD30 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Hodgkin's Lymphoma. Localization: Membranous
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
CD30 is a transmembrane cytokine receptor belonging to the tumor necrosis factor (TNF) receptor super- family. Mature CD30 has a molecular mass of 120 kDa and is derived from a 90 kDa precursor protein. CD30 antibody detects an epitope which is expressed by Reed-Sternberg cells in Hodgkin's Disease, the majority of Anaplastic Large-cell Lymphomas, and in Embryonal Carcinomas and Seminomas. This antibody also stains plasma cells intensely in paraffin-embedded tissue.
ncbi gi num :
180096
uniprot acc num :
P28908
ncbi mol weight :
63,747 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!TNF-alpha/NF-kB Signaling Pathway 198884
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
uniprot summary :
Function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. Subunit structure: Interacts with TRAF1, TRAF2, TRAF3 and TRAF5. Ref.8 Ref.9 Ref.10 Ref.11. Subcellular location: Isoform Long: Cell membrane; Single-pass type I membrane protein. Isoform Short: Cytoplasm. Post-translational modification: Phosphorylated on serine and tyrosine residues. Ref.12. Miscellaneous: Most specific Hodgkin disease associated antigen. Sequence similarities: Contains 6 TNFR-Cys repeats.
size :
3 ml
price :
200 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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