catalog number :
MBS370017
products full name :
CD123, IL-3Ra
products short name :
CD123, IL-3Ra
products gene name :
CD123
form :
CD123 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative.
storage stability :
Store at 2 to 8 degree C in the dark.
other info1 :
Control: Tonsil, Lymph Node, Kikuchi-Fujimoto Disease. Localization: Membranous
other info2 :
Reactivity Note: Paraffin, Frozen
products description :
CD123 is alpha chain of the IL-3 receptor. This 60-70 kDa transmembrane protein, by itself, binds to IL-3 with rather low affinity. However, when associated with CD131 (common beta chain), the protein binds to IL-3 with high affinity. The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes. The receptor belongs to the Type I cytokine-receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. The CD123 receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.
size1 :
5 + Control Slides
size2 :
3 ml (Prediluted)
size3 :
0.1 mL (Concentrate)
size4 :
7 ml (Prediluted)
size5 :
0.5 mL (Concentrate)