catalog number :
MBS355650
products type :
Recombinant Protein
products full name :
PGA pepsinogen I, PGI Protein (Active)
products short name :
PGA pepsinogen I, PGI
other names :
Pgi; Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); hypothetical protein; Phosphoglucose isomerase; PGI; Phosphohexose isomerase
other gene names :
pgi; pgi; GPI; PGI; PHI
uniprot entry name :
G6PI_DESAH
purity :
>95% by SDS-PAGE
storage stability :
Ship at 4 degree C. Upon receipt, aliquot and store at -20 degree C or -80 degree C for long term. Avoid repeated freeze and thaw cycles.
tested application :
SDS-PAGE
other info2 :
Storage Buffer: Each vial contains 10 mM Tris-HCl (pH7.5) without preservative.
products description :
Recombinant human PG I protein. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41-amino acid segment from the amino end. There are 2 related pepsinogen systems in man: PGA, formerly PG I, precursor of pepsin A, and PGC, formerly PG II, precursor of pepsin C. In human gastric mucosa, 2 immunologically distinct classes of pepsinogen are synthesized. PG1 is restricted to the corpus, while PG2 is found throughout the stomach as well as in the proximal duodenum. PG1 is found in serum and urine in a ratio of about 1 to 10. PG2 is present in serum and seminal fluid but only trace amounts are found in urine. Serum PG1 and PG2 apparently originate from the stomach in the main, because the levels are very low after gastrectomy. PG2 in seminal fluid probably originates from the prostate.
ncbi acc num :
ACN16241.1
ncbi mol weight :
61,596 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway (92456); Amino Sugar And Nucleotide Sugar Metabolism Pathway (350); Biosynthesis Of Secondary Metabolites Pathway (149704); Carbon Metabolism Pathway (815371); Carbon Metabolism Pathway (817567); Glycolysis (Embden-Meyerhof Pathway), Glucose = Pyruvate (399406); Glycolysis (Embden-Meyerhof Pathway), Glucose = Pyruvate (468194); Glycolysis / Gluconeogenesis Pathway (92416); Glycolysis / Gluconeogenesis Pathway (287); Microbial Metabolism In Diverse Environments Pathway (180644)
uniprot summary :
Catalytic activity: D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473. Pathway: Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00473Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473. Subcellular location: Cytoplasm . By similarity HAMAP-Rule MF_00473. Sequence similarities: Belongs to the GPI family.