catalog number :
MBS355629
products type :
Recombinant Protein
products full name :
HBcAg Protein
products short name :
HBcAg
other names :
HBcAg, partial
products gene name :
HBcAg
purity :
>90% by SDS-PAGE
concentration :
1.5 mg/ml
storage stability :
Ship at 4 degree C. Upon receipt, store at -20 degree C or -80 degree C for 2 years. After reconstituting, it can store at 4 degree C for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
tested application :
ELISA (EIA)
app notes :
ELISA (EIA). Other applications have not been tested. The optimal dilutions should be determined by the end user.
other info2 :
Inactivation: Heated for 10 hours at 60 degree C before ultracentrifugation. Storage Buffer: Each vial contains 0.02 M sodium phosphate (pH7.2) without preservative.
products description :
Recombinant full length human Hepatitis BcAg protein. HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). Hepatitis B virus (HBV) core antigen (HBcAg)-specific CD4(+) T-cell responses are believed to play an important role in the control of human HBV infection. HBcAg-specific CD4(+) Th1-type T cells can modulate the function and exert a regulatory role in deleting HBcAg-binding, or -specific, human B cells in vivo, which may be of importance in controlling the infection.
products references :
1. Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA". J. Clin. Microbiol. 41 (5): 1901-6. 2. Cao T, Meuleman P, Desombere I, Sällberg M, Leroux-Roels G (December 2001). "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model". J. Virol. 75 (23): 11449-56.
ncbi acc num :
CCQ25628.1