protein

Human albumin Protein (Active)

MBS355522

1 mg

300 USD

Native Protein

Human albumin Protein (Active)

albumin

Human albumin

albumin; Serum albumin; serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42; albumin

ALB; ALB; PRO0883; PRO0903; PRO1341

ALBU_HUMAN

Human serum

>90% by SDS-PAGE

Lyophilized or Liquid (please inquire) "lot specific

Ship at 4 Degree C. Upon receipt, store at -20 Degree C for 3 years. After reconstitution, aliquot and store at -20 Degree C or -80 degree C for long-term storage. Avoid repeated freeze and thaw cycles.

ELISA (EIA)

ELISA. Other applications have not been tested.

Reconstitution: Reconstitute the lyophilized albumin protein with neutral PBS to the needed concentration.

Background: Albumin is a soluble, monomeric protein of molecular weight 65,000, which comprises about one-half of the blood serum protein. The albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site.[1] It is synthesized in the liver as preproalbumin, which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume.

178344

AAA98797.1

P02768

Bile Acid And Bile Salt Metabolism Pathway (106144); Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation, Signaling And Aggregation Pathway (106034)

Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]

Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Ref.32. Subcellular location: Secreted. Tissue specificity: Plasma. Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracellular medium.Acetylated on Lys-223 by acetylsalicylic acid. Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A. Involvement in disease: Familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]: Form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.61 Ref.62 Ref.63 Ref.64. Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains. Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulate fat digestion, lipid absorption, and blood flow. Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

1 mg

300 USD