protein

Troponin I Protein (Active)

MBS355513

0.1 mg

335 USD

Native Protein

Troponin I Protein (Active)

Troponin I

Troponin I; cardiac muscle; TnIc; Cardiac Troponin I; cTnI; TNNI3; TNNC1

troponin I; troponin I

LOC100136571

Human heart tissue

Liquid

2 mg/ml

Ship at 4 degree C. Upon receipt, aliquot and store at -20 degree C or -80 degree C for long term. Avoid repeated freeze and thaw cycles.

ELISA (EIA)

ELISA. Other applications have not been tested.

Storage Buffer: Each viale contains Tris buffer (pH 7.5) without preservative.

Background/Introduction: Troponin I is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle, the others are troponin T and troponin C. Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. It binds actin and inhibits actomyosin ATPase activity in the absence of calcium. In 2000, Labarrere et al. found that persistent elevation of cardiac troponin I levels after heart transplantation were associated with high risk for 'developing coronary artery disease and graft failure after cardiac transplantation. The cardiac troponin I may be a useful tool in identifying patients with heart failure who are at increased risk for progressive ventricular dysfunction and death.

185132467

NP_001117133.1

NM_001123661.1

0.1 mg

335 USD