catalog number :
MBS355010
products full name :
D-dimer (Detection Ab)
products short name :
D-dimer mAb (Mouse anti-human, clone # D10)-Detection Ab
products name syn :
Monoclonal Anti- D-dimer (Detection Ab)
specificity :
It specifically recognize human D-dimer antigen, and does not cross react with BSA, but has week cross-reactivity with fibrinogen.
purity :
Protein A or G purified and supplied in 0.01 M PBS (pH7.4) without preservative. >95% by HPLC & SDS-PAGE
storage stability :
Aliquot and store at -20 degree C for long term (at least one year). Avoid repeated freeze and thaw cycles.
tested application :
Western Blot (WB), Lateral Flow (LF), ELISA (EIA)
app notes :
WB, ELISA, Lateral flow assay (rapid test)
other info1 :
Immunogen: Human D-dimer protein.
other info2 :
Matched Antibody Pairs: Capture Ab: D-dimer mAb (clone # C6) or D-dimer mAb (clone # C9). Detection Ab: D-dimer mAb (clone # D10)
products description :
D-dimer is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two crosslinked D fragments of the fibrin protein. The D-dimer antigen is a unique marker of fibrin degradation that is formed by the sequential action of 3 enzymes: thrombin, factor XIIIa, and plasmin. Its concentration may be determined by a blood test to help diagnose thrombosis. Since its introduction in the 1990s, it has become an important test performed in patients suspected of thrombotic disorders. While a negative result practically rules out thrombosis, a positive result can indicate thrombosis but does not rule out other potential causes. Its main use, therefore, is to exclude thromboembolic disease where the probability is low. In addition, it is used in the diagnosis of the blood disorder disseminated intravascular coagulation.
products references :
1. Adam SS, Key NS, Greenberg CS (March 2009). "D-dimer antigen: current concepts and future prospects". Blood 113 (13): 2878-2887.