product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit Anti-human Osteocalcin (40-49) Sera
catalog :
MBS352204
quantity :
0.1 mL
price :
270 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS352204
products type :
Antibody
products full name :
Rabbit Anti-human Osteocalcin (40-49) Sera
products short name :
Osteocalcin [40-49]
products name syn :
Osteocalcin [40-49]
other names :
osteocalcin preproprotein; Osteocalcin; osteocalcin; bone Gla protein; OTTHUMP00000016586; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
other gene names :
BGLAP; BGLAP; OC; BGP
uniprot entry name :
OSTCN_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
specificity :
Polypeptide ::: % Cross Reactivity . Osteocalcin (40-49) ::: 100. Osteocalcin ::: 100. Osteocalcin (Bovine) ::: 40
form :
Antiserum Specificity
tested application :
Histo
products categories :
Histochemical Grade Antibodies
products description :
These antisera were raised in rabbits which were immunized with Human Osteocalcin (40-49) covalently attached onto a carrier protein. The antisera have been shown to be specific for the immunocytochemical detection of Osteocalcin (40-49). This antisera has been characterized by ELISA techniques. Dilute the lyophilized antibody with 0.1 ml of 10 mg/ml BSA in PBS for the equivalent of whole antiserum. or with additional buffer for more dilute antibody.
ncbi gi num :
40316933
ncbi acc num :
NP_954642.1
ncbi gb acc num :
NM_199173.4
uniprot acc num :
P02818
ncbi mol weight :
10,963 Da
ncbi pathways :
Cell Cycle, Mitotic Pathway (105765); DNA Replication Pathway (105897); FGF Signaling Pathway (137989); Glucocorticoid Receptor Regulatory Network Pathway (138014); M Phase Pathway (105812); Mitotic M-M/G1 Phases Pathway (160943); Mitotic Prometaphase Pathway (105815); Notch-mediated HES/HEY Network Pathway (169347); Regulation Of Retinoblastoma Protein Pathway (137916); Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway (169349)
ncbi summary :
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
uniprot summary :
Function: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Subcellular location: Secreted. Post-translational modification: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. Sequence similarities: Belongs to the osteocalcin/matrix Gla protein family.Contains 1 Gla (gamma-carboxy-glutamate) domain.
size1 :
0.1 mL
price1 :
270 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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