product summary
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company name :
MyBioSource
product type :
protein
product name :
Kallikrein 6 (KLK-6)
catalog :
MBS343204
quantity :
0.01 mg
price :
220 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS343204
products type :
Recombinant Protein
products full name :
Kallikrein 6 (KLK-6)
products short name :
Kallikrein 6 (KLK-6)
products name syn :
KLK-6; Kallikrein-Related Peptidease 6; Protease Serine 9; Prss9; Protease M; Neurosin; SP59; Serine Protease 18.
other names :
kallikrein-6 isoform B; Kallikrein 6 variant 4; kallikrein-6; kallikrein related peptidase 6; Kallikrein 6 variant 4
products gene name :
KLK-6
other gene names :
KLK6; KLK6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
uniprot entry name :
Q6JIA6_HUMAN
sequence length :
137
purity :
>95% by SDS-PAGE
form :
Liquid
other info2 :
Buffer: Buffered 50% glycerol
products categories :
Recombinant Proteins; Kallikrein 6
products description :
Kallikreins are a subgroup of serine proteases having diverse physiological functions, from carcinogenesis to novel cancer biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The KLK-6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Recombinant Kallikrein-6 comprises a 230 amino acid fragment (15- 244) corresponding to the mature Kallikrein-6 protein and is expressed in E Coli with an amino-terminal hexahistidine tag. This product is not intended for therapeutic use.
products references :
Yousef GM, et.al (2003). Clin. Chim. Acta 329 (1-2): 1 -8.
ncbi gi num :
61744426
ncbi acc num :
NP_001012983.1
ncbi gb acc num :
NM_001012965.2
uniprot acc num :
Q6JIA6
ncbi mol weight :
13,078 Da
ncbi pathways :
Alpha-synuclein Signaling Pathway (137913)
ncbi summary :
This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
size1 :
0.01 mg
price1 :
220 USD
size2 :
0.1 mg
price2 :
555
size3 :
1 mg
price3 :
2535
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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