catalog number :
MBS343171
products type :
Recombinant Protein
products full name :
Pro-Matrix Metalloproteinase 9 (Western Blot Control)
products short name :
Pro-Matrix Metalloproteinase 9 (Western Blot Control)
products name syn :
Pro-MMP 9; Pro- Matrix Metalloproteinase 9 (Pro-MMP 9); Matrix metalloproteinase 9, gelatinase B, 92kD gelatinase, 92kD type IV collagenase precursor,CLG4B, GELB
other names :
pro-MMP-9; Pro-MMP-9; matrix metalloproteinase-9; GELB; Gel B; gelatinase B; 92kD gelatinase; 92kDa gelatinase; 92 kDa gelatinase; OTTMUSP00000001145; collagenase type IVB; 92kD type IV collagenase; 92kDa type IV collagenase; 92 kDa type IV collagenase; matrix metalloproteinase 9; matrix metallopeptidase 9
products gene name :
Pro-MMP 9
other gene names :
Mmp9; Mmp9; Clg4b; MMP-9; B/MMP9; AW743869; pro-MMP-9
uniprot entry name :
Q91ZS5_MOUSE
purity :
Single band on Western blot
form :
Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
products categories :
Human Recombinant Protein
products description :
Matrix metalloproteinases are a family of zinc- and calcium-dependant endopeptidases, which degrade extracellular matrix proteins. MMP-9 is secreted as a 92kDa zymogen. Cleavage of pro-MMP-9 results in the active enzyme with a molecular weight of ~82kDa. MMP-9 has a gelatin-binding domain consisting of three fibronectin type II units, a catalytic domain containing the zinc-binding site, a proline-rich type V collagen-homologous domain and a hemopexin-like domain. MMP9 is produced by monocytes, macrophages, neutrophils, keratinocytes, fibroblasts, osteoclasts and endothelial cells, and is involved in inflammatory responses, tissue remodelling, wound healing, tumour growth and metastasis. Our recombinant human Pro-MMP-9 comprises a 688aa fragment (20-707) corresponding to the pro form of the protein minus the signal peptide and is expressed in E. coli with an N-terminal 6xHis tag. This product is for research use only and is not intended for diagnostic or therapeutic use
products references :
Pourmotabbed, T et al., Biochim Biophys Acta. 1204 (1):97-107(1994). Romanic, AM. et al., Stroke 29 (5): 1020-1030 (1998).
ncbi mol weight :
6,347 Da
ncbi pathways :
Bladder Cancer Pathway 83308!!Bladder Cancer Pathway 527!!Endochondral Ossification Pathway 198336!!IL-3 Signaling Pathway 198420!!Leukocyte Transendothelial Migration Pathway 83280!!Leukocyte Transendothelial Migration Pathway 494!!Matrix Metalloproteinases Pathway 198370!!Pathways In Cancer 83298