This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
Tumour Necrosis Factor Beta (Western Blot Control)
catalog :
MBS343143
quantity :
0.01 mg
price :
190 USD
product information
catalog number :
MBS343143
products type :
Recombinant Protein
products full name :
Tumour Necrosis Factor Beta (Western Blot Control)
products short name :
Tumour Necrosis Factor Beta (Western Blot Control)
products name syn :
TNFb; TNF beta; Tumour necrosis factor beta, Lymphotoxin alpha, LT alpha , TNF beta , TNFSF1, TNF superfamily - member 1
other names :
Tumour necrosis factor beta; Lymphotoxin-alpha; lymphotoxin-alpha; LT-alpha; TNF-beta; tumour necrosis factor beta; tumor necrosis factor ligand superfamily member 1; TNF-beta; Tumor necrosis factor ligand superfamily member 1
products gene name :
TNFb
other gene names :
LTA; LTA; TNFB; TNFB; TNFSF1
uniprot entry name :
TNFB_PIG
sequence length :
204
purity :
Single band on Western blot
form :
Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
products categories :
Human Recombinant Protein
products description :
TNF beta is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumour cells and a variety of other target cells as well as being a mediator of inflammation and immune function. Our recombinant TNF beta comprises a 171 amino acid fragment (35-205) corresponding to the mature TNF beta chain protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
products references :
Ruddle, N.H. (1992) Curr. Opin. Immunol. 4(3) : 327-332. Porter, A.G. (1990) FEMS Microbiol. Immunol. 2(4) : 193- 199.
ncbi gi num :
2133
ncbi acc num :
CAA38638.1
uniprot acc num :
P26445
ncbi mol weight :
21,960 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 84463!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373897!!HTLV-I Infection Pathway 373889!!Type I Diabetes Mellitus Pathway 84506!!Type I Diabetes Mellitus Pathway 507
uniprot summary :
Function: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. Subunit structure: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Subcellular location: Secreted. By similarity. Membrane. By similarity. Note: The homotrimer is secreted. By similarity. The heterotrimer is membrane-associated. Sequence similarities: Belongs to the tumor necrosis factor family.
size :
0.01 mg
price :
190 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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