antibody

Meprobamate

MBS340534

0.1 mL

600 USD

polyclonal

sheep

nonconjugated

western blot, ELISA, immunohistochemistry, enzyme immunoassay

Antibody

Meprobamate

Meprobamate

Miltown; Equanil; Meprospan

Polyclonal

Sheep

Ig Fraction - Liquid

>5mg/ml (U.V.abs @ 280nm)

Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.

ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays

Immunogen: Meprobamate-BTG

Buffer: 20mM Phosphate, 150mM Sodium Chloride. Preservative: 0.09% Sodium Azide

Polyclonal Antibodies; Drugs of Abuse; Sedatives; Meprobamate

Meprobamate (marketed under the brand names Miltown by Wallace Laboratories, Equanil by Wyeth, and Meprospan) is a carbamate derivative which is used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines. Although it was marketed as being safer, meprobamate has most of the pharmacological effects and dangers of the barbiturates (though it is less sedating at effective doses). It is reported to have some anticonvulsant properties against absence seizures, but can exacerbate generalized tonic-clonic seizures. Meprobamate's mechanism of action is not completely known. It has been shown in animal studies to have effects at multiple sites in the central nervous system, including the thalamus and limbic system. Meprobamate binds to GABAA receptors which interrupts neuronal communication in the reticular formation and spinal cord, causing sedation and altered perception of pain. It has been shown that meprobamate has the ability to activate currents even in the absence of GABA. It is also a potent adenosine reuptake inhibitor (AdoRI).

0.1 mL

600 USD

1 mL

3005