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company name :
MyBioSource
product type :
antibody
product name :
Neuronal Specific Enolase (NSE)
catalog :
MBS340310
quantity :
1 mL
price :
465 USD
clonality :
polyclonal
host :
sheep
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS340310
products type :
Antibody
products full name :
Neuronal Specific Enolase (NSE)
products short name :
Neuronal Specific Enolase (NSE)
products name syn :
Enolase 2; Neuronal specific enolase; EC. 4.2.1.11; 2-phospho-Dglycerate hydrolyase; enolase 2 (gamma neuronal); neuron specific enolase; neural enolase
other names :
neurone-specific enolase, partial; Gamma-enolase; gamma-enolase; enolase 2; 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE
products gene name :
NSE
other gene names :
ENO2; ENO2; NSE; HEL-S-279; NSE
uniprot entry name :
ENOG_HUMAN
clonality :
Polyclonal
host :
Sheep
sequence length :
433
form :
Ig Fraction - Liquid
concentration :
>5mg/ml (U.V.abs @ 280nm)
storage stability :
Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays
other info1 :
Immunogen: Recombinant Human NSE
other info2 :
Buffer: 20mM Phosphate, 150mM Sodium Chloride. Preservative: 0.09% Sodium Azide
products categories :
Polyclonal Antibodies; Biochemical Markers; Proteins; Neuronal Specific Enolase
products description :
NSE is the isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival. Recombinant NSE comprises a 433 amino acid fragment (2-434) corresponding to processed mature NSE protein and is expressed in E Coli with an aminoterminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
products references :
Kaiser, E. et al.,(1989) Clin. Chim. Acta. 183 (1):13-3
ncbi gi num :
930063
ncbi acc num :
CAA31512.1
uniprot acc num :
P09104
ncbi mol weight :
42,707 Da
ncbi pathways :
Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Gluconeogenesis Pathway (1269961); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196); Glucose Metabolism Pathway (1269959); Glycolysis Pathway (1269960); Glycolysis (Embden-Meyerhof Pathway), Glucose = Pyruvate (413340)
ncbi summary :
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]
uniprot summary :
ENO2: an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Protein type: Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 4.2.1.11. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: cytosol; extracellular space. Molecular Function: phosphopyruvate hydratase activity; protein binding. Biological Process: gluconeogenesis
size1 :
1 mL
price1 :
465 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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