product summary
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company name :
MyBioSource
product type :
antibody
product name :
L-Selectin
catalog :
MBS340243
quantity :
1 ml
price :
350 USD
clonality :
polyclonal
host :
sheep
conjugate :
nonconjugated
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS340243
products type :
Antibody
products full name :
L-Selectin
products short name :
L-Selectin
products name syn :
Anti - L-Selectin
other names :
L-selectin; L-selectin; L-selectin; gp90-MEL; OTTHUMP00000032696; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1; selectin L; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL
other gene names :
SELL; SELL; TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1; LNHR; LYAM1
uniprot entry name :
LYAM1_HUMAN
clonality :
Polyclonal
host :
Sheep
sequence length :
372
form :
Ig fraction, liquid
storage stability :
Store at -20 degree C. Avoid repeated freeze/thaw cycles.
other info1 :
Immunogen: Recombinant Human L-Selectin
other info2 :
Buffer: 20mM Phosphate, 150mM Sodium Chloride, pH 7.2. Preservative: 0.09% Sodium Azide
ncbi gi num :
5852072
ncbi acc num :
CAB55488.1
uniprot acc num :
Q9UJ43
ncbi mol weight :
42,187 Da
ncbi pathways :
Adaptive Immunity Signaling Pathway 366160!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Hemostasis Pathway 106028!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413
ncbi summary :
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
uniprot summary :
Function: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Ref.10. Subunit structure: Interaction with PSGL1/SELPLG and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of PSGL1 and PODXL2, and tyrosine sulfation modifications of PSGL1. Sulfation on Y-51 of PSGL1 is important for L-selectin binding. Subcellular location: Membrane; Single-pass type I membrane protein. Tissue specificity: Expressed in B cell lines and T lymphocytes. Ref.2. Sequence similarities: Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 2 Sushi (CCP/SCR) domains. Sequence caution: The sequence CAA34203.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAB43536.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAB43537.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
size :
1 ml
price :
350 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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