catalog number :
MBS340106
products full name :
Dehydroepiandrosterone Sulphate (DHEA-S)
products short name :
Dehydroepiandrosterone Sulphate (DHEA-S)
products name syn :
Dehydroepiandrosterone; 5-DHEA
products gene name :
DHEA-S
form :
Ig Fraction - Liquid
concentration :
>5mg/ml (U.V.abs @ 280nm)
storage stability :
Upon delivery aliquot and store at -20 degree C. Avoid freeze / thaw cycles. Short term storage 2 - 8 degree C.
tested application :
ELISA (EIA), Western Blot (WB), Dot Blot (DB), Immunohistochemistry (IHC), Immunoassays, Development of Rapid tests and Other Immunoassay, Antibody Recognition Assays
other info1 :
Immunogen: DHEA-S-BTG
other info2 :
Buffer: 20mM Phosphate, 150mM Sodium Chloride. Preservative: 0.09% Sodium Azide
products categories :
Polyclonal Antibodies; Growth Promoters; Natural Steroids; Dehydroepiandrosterone
products description :
Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS). DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver. DHEA in adults is present at plasma concentrations 100 to 500 times higher than those of testosterone. DHEA can be metabolized to androgens and/or estrogens in the prostate. Hepatic metabolites include 16beta-hydroxy-DHEA, 7beta-hydroxy-DHEA, and 7-oxo-DHEA. 7beta-OH-DHEA is a metabolite. The major metabolite produced in humans is a mono-hydroxylated DHEA species. Synthesis of a 7beta-hydroxy-DHEA and 5-androstene-3beta, 17beta-diol occurs in the frontal cortex, hippocampus, amygdala, cerebellum and striatum.