Human IFN gamma ELISA Set | MyBioSource MBS335535 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human IFN gamma ELISA Set

catalog :

MBS335535

quantity :

1 x96 Wells

price :

205 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS335535

products type :

ELISA Set

products full name :

Human IFN gamma ELISA Set

products short name :

IFN gamma

products name syn :

IFN-g

other names :

interferon gamma; Interferon gamma; interferon gamma; interferon gamma

products gene name :

IFN gamma

other gene names :

Ifng; Ifng; Ifg; IFN-g; IFN-gamma

uniprot entry name :

IFNG_MOUSE

reactivity :

Human. No cross reactivity with other human cytokines. Cross reactivity with simian IFN-g.

sequence length :

155

specificity :

Recognizes both natural and recombinant human IFN-g

other info1 :

Sensitivity: The sensitivity, minimum detectable dose of this IFNg antibody pair was determined using the IFNg ELISA kit (which contains the same antibodies) and was found to be <5pg/ml. This was determined by adding 3 standard deviations to the mean OD obtained when the zero standard was assayed 40 times.

products categories :

Human ELISA Sets

products description :

MyBioSource ELISA Sets include capture and biotinylated detection antibody, one standard per plate, Streptavidin-HRP, TMB, and detailed procedure including buffer composition.

products references :

Audran, R. et al., Infect Immun., 2005; 73(12): 8017-26. Filaci, G. et al., J. Immunol.,2007; 179(7): 4323-4334. Haller D. et al., Clin. Diagn. Lab. Immunol., 2002; 9(3): 649 - 657

ncbi gi num :

33468859

ncbi acc num :

NP_032363.1

ncbi gb acc num :

NM_008337.3

uniprot acc num :

P01580

ncbi mol weight :

17,907 Da

ncbi pathways :

African Trypanosomiasis Pathway (194387); African Trypanosomiasis Pathway (194323); Allograft Rejection Pathway (83316); Allograft Rejection Pathway (535); Amoebiasis Pathway (167330); Amoebiasis Pathway (167191); Antigen Processing And Presentation Pathway (83271); Antigen Processing And Presentation Pathway (485); Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795)

ncbi summary :

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015]

uniprot summary :

IFNG: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Homodimer. Released primarily from activated T lymphocytes. Belongs to the type II (or gamma) interferon family. Protein type: Secreted; Secreted, signal peptide; Membrane protein, integral; Cytokine. Cellular Component: extracellular space; cell; extracellular region; intracellular; external side of plasma membrane. Molecular Function: protein binding; interferon-gamma receptor binding; cytokine activity. Biological Process: positive regulation of isotype switching to IgG isotypes; positive regulation of cell adhesion; positive regulation of nitric oxide biosynthetic process; positive regulation of osteoclast differentiation; positive regulation of interleukin-23 production; positive regulation of transcription, DNA-dependent; negative regulation of epithelial cell differentiation; positive regulation of killing of cells of another organism; positive regulation of interleukin-1 beta secretion; positive regulation of membrane protein ectodomain proteolysis; regulation of growth; positive regulation of T cell proliferation; cell cycle arrest; defense response to virus; regulation of the force of heart contraction; positive regulation of peptidyl-serine phosphorylation of STAT protein; neutrophil chemotaxis; positive regulation of synaptic transmission, cholinergic; CD8-positive, alpha-beta T cell differentiation during immune response; negative regulation of myelination; response to virus; positive regulation of tumor necrosis factor production; defense response to protozoan; inflammatory cell apoptosis; positive regulation of tyrosine phosphorylation of Stat1 protein; defense response to bacterium; neutrophil apoptosis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-12 production; negative regulation of smooth muscle cell proliferation; apoptosis; positive regulation of interleukin-6 biosynthetic process; sensory perception of mechanical stimulus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; regulation of transcription, DNA-dependent; positive regulation of MHC class II biosynthetic process; positive regulation of cell proliferation; adaptive immune response; regulation of immune response; unfolded protein response; humoral immune response; antigen processing and presentation; positive regulation of interleukin-12 biosynthetic process; positive regulation of chemokine biosynthetic process; negative regulation of interleukin-17 production; protein import into nucleus, translocation; immune response; positive regulation of neuron differentiation; regulation of insulin secretion

size1 :

1 x96 Wells

price1 :

205 USD

size2 :

5x96 Wells

price2 :

405

size3 :

10x96 Wells

price3 :

505

size4 :

15x96 Wells

price4 :

575

size5 :

20x96 Wells

price5 :

675

more info or order :

MyBioSource product webpage