product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-Human IL-33 Monoclonal Antibody, Azide Free Clone B-L33
catalog :
MBS335425
quantity :
0.5 mg
price :
505 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
B-L33
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS335425
products type :
Antibody
products full name :
Mouse Anti-Human IL-33 Monoclonal Antibody, Azide Free Clone B-L33
products short name :
IL-33
products name syn :
IL-33
other names :
interleukin-33 isoform 3; Interleukin-33; interleukin-33; interleukin 33; Interleukin-1 family member 11; IL-1F11
products gene name :
IL-33
other gene names :
IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV
uniprot entry name :
IL33_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
B-L33
host :
Mouse
reactivity :
Human
sequence length :
144
specificity :
Recognises both natural and recombinant human IL-33
purity :
Ion exchange chromatography
form :
Azide free. Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
storage stability :
Stable at +2-8 degree C for 12 months. For longer storage, freeze aliquots.
tested application :
ELISA (EIA)
app notes :
Recognises soluble antigen
other info2 :
Antigen: IL-33. Hybridoma: Myeloma X63/AG.8653 x Balb/c lymph node cells. Immunisation: Recombinant human IL-33/NF-HEV
ncbi gi num :
314122337
ncbi acc num :
NP_001186570.1
ncbi gb acc num :
NM_001199641.1
uniprot acc num :
O95760
ncbi mol weight :
16,250 Da
ncbi pathways :
Cytosolic DNA-sensing Pathway (125137); Cytosolic DNA-sensing Pathway (124833); Influenza A Pathway (217173); Influenza A Pathway (217150)
ncbi summary :
IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]
uniprot summary :
IL33: Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T-helper type 2-associated cytokines. Belongs to the IL-1 family. Highly divergent. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cytokine. Chromosomal Location of Human Ortholog: 9p24.1. Cellular Component: extracellular space; transport vesicle; chromosome; nucleus. Molecular Function: protein binding; cytokine activity. Biological Process: T-helper 2 type immune response; positive regulation of T-helper 2 type immune response; negative regulation of T-helper 1 type immune response; transcription, DNA-dependent; positive regulation of interleukin-6 production; positive regulation of immunoglobulin secretion; negative regulation of leukocyte migration; positive regulation of interleukin-4 production; negative regulation of immunoglobulin secretion; negative regulation of interferon-gamma production; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of interleukin-13 production; positive regulation of interleukin-5 production; positive regulation of macrophage activation; positive regulation of inflammatory response
size1 :
0.5 mg
price1 :
505 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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