product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse Anti-Human CD2 Monoclonal Antibody, FITC Conjugated Clone B-E2
catalog :
MBS335155
quantity :
100 Tests
price :
310 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
[B-E2]
reactivity :
human
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS335155 image 1
A typical staining pattern with the B-E2 monoclonal antibody of lymphocytes
product information
catalog number :
MBS335155
products type :
Antibody
products full name :
Mouse Anti-Human CD2 Monoclonal Antibody, FITC Conjugated Clone B-E2
products short name :
[CD2]
products name syn :
[CD2; LFA-2]
other names :
[CD2 surface antigen; T-cell surface antigen CD2; T-cell surface antigen CD2; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]
products gene name :
[CD2]
other gene names :
[CD2; CD2; T11; SRBC; LFA-2; SRBC]
uniprot entry name :
CD2_HUMAN
clonality :
Monoclonal
isotype :
Mouse IgG2b Kappa light chain
clone :
[B-E2]
host :
Mouse
reactivity :
Human
sequence length :
360
specificity :
Recognises the Lymphocyte Function associated Antigen-2 (LFA-2), a 50 kDa protein
purity :
Ion exchange chromatography
form :
Phosphate-buffered saline with 5% BSA and 0.09% sodium azide
storage stability :
Stable at +2-8 degree C for 12 months. For longer storage freeze aliquots.
tested application :
Flow Cytometry (FC/FACS)
app notes :
Working Dilution: Use 10 ul to label 10 6 cells or 100 mul of whole blood.
image1 heading :
Testing Data
other info1 :
Workshop: V
other info2 :
Antigen: CD2 / LFA-2. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells. Immunisation: Human thymocytes. Conjugation: FITC
products references :
Douglas et.al. J Immunol 2000
ncbi gi num :
180094
ncbi acc num :
AAA51946.1
uniprot acc num :
P06729
ncbi mol weight :
39,448 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Hemostasis Pathway (1269340)
ncbi summary :
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
uniprot summary :
CD2: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. Protein type: Cell surface; Membrane protein, integral; Apoptosis. Chromosomal Location of Human Ortholog: 1p13.1. Cellular Component: internal side of plasma membrane; anchored to plasma membrane; cell surface; integral to plasma membrane; plasma membrane; extracellular region; intercellular junction; external side of plasma membrane. Molecular Function: protein binding; protein homodimerization activity; receptor activity; receptor binding. Biological Process: heterotypic cell-cell adhesion; cell-cell adhesion; cell surface receptor linked signal transduction; T cell activation; apoptosis; natural killer cell activation; regulation of T cell differentiation; blood coagulation; lipid raft polarization; positive regulation of tumor necrosis factor production; positive regulation of myeloid dendritic cell activation; leukocyte migration
size1 :
100 Tests
price1 :
310 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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