catalog number :
MBS3246345
products type :
Blocking Peptide
products full name :
AKAP12 Peptide - middle region
products short name :
[AKAP12]
other names :
[A-kinase anchor protein 12 isoform 1; A-kinase anchor protein 12; A-kinase anchor protein 12; A-kinase anchoring protein 12; A-kinase anchor protein 250 kDa; AKAP 250; Gravin; Myasthenia gravis autoantigen]
products gene name :
[AKAP12]
products gene name syn :
[SSeCKS; AKAP250]
other gene names :
[AKAP12; AKAP12; SSeCKS; AKAP250; AKAP250; AKAP-12; AKAP 250]
uniprot entry name :
AKA12_HUMAN
sequence :
MLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG
DEESGEHTQVP
Synthetic peptide located within the following region:
form :
Lyophilized powder
storage stability :
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
products categories :
Peptide
products description :
This is a synthetic peptide designed for use in combination with anti- AKAP12 Antibody, made. Target Description: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
ncbi acc num :
NP_005091.2
ncbi gb acc num :
NM_005100.3
ncbi mol weight :
185 kDa
ncbi pathways :
G Protein Signaling Pathways (198849)
ncbi summary :
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]