catalog number :
MBS319259
products type :
Recombinant Protein
products full name :
CK-MM Type III, Recombinant
products short name :
Creatine Kinase MM (CK-MM) Type III, Recombinant
products name syn :
CK-MM Type 3, Recombinant; Creatine Kinase MM (CK-MM) Type 3 Isoenzyme Recombinant
other names :
creatine kinase; Creatine kinase M-type; creatine kinase M-type; creatine kinase-M; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CK
other gene names :
CKM; CKM; CKMM; M-CK; CKMM
uniprot entry name :
KCRM_HUMAN
specificity :
Creatine Kinase MM (CK-MM) Type III, Recombinant
purity :
>95% pure (SDS-PAGE). Purified under non-denaturing conditions.
storage stability :
Store at -70 degree C or below. Aliquot to avoid multiple freeze/thaw cycles.
other info1 :
Inactivation: Not applicable
other info2 :
Buffer: Tris-buffered saline (TBS), 10mM beta-mercaptoethanol, 50% glycerol, pH 7.0-7.5. Preservative: 0.1% Sodium azide. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Purified Cardiac Markers
products description :
Creatine Kinase MM isoenzyme with identical amino acid sequence to that of the native enzyme. CK-MM is a 47 kDa dimeric protein comprised of 2 identical subunits. Purified in the enzymatically active form. Reacts with polyclonal antibodies to MM isoenzyme
ncbi acc num :
AAA96609.1
ncbi mol weight :
43,101 Da
ncbi pathways :
Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Creatine Metabolism Pathway 106192!!Metabolic Pathways 132956!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Regulation Of Retinoblastoma Protein Pathway 137916!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758!!Creatine-phosphate Biosynthesis Pathway 138632
ncbi summary :
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq]
uniprot summary :
Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.