catalog number :
MBS319026
products type :
Recombinant Protein
products full name :
Human Epidermal Growth Factor, Recombinant
products short name :
Epidermal Growth Factor, Recombinant
other names :
epidermal growth factor; Epidermal growth factor; pro-epidermal growth factor; beta-urogastrone; OTTHUMP00000162922; OTTHUMP00000219721; OTTHUMP00000219722; epidermal growth factor
other gene names :
EGF; EGF; URG; HOMG4
uniprot entry name :
Q6QBS2_HUMAN
specificity :
Epidermal Growth Factor, Recombinant
purity :
>98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE). Endotoxin level is less than 0.1ng/ug (IEU/ug). Purified by chromatographic techniques. Product is sterile filtered.
form :
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >100ug/ml. Further dilutions can be made in other aqueous buffers.
concentration :
1mg/ml (OD280nm, E0.1% = 2.858) (prior to lyophilization)
storage stability :
The lyophilized product, though stable for 3 weeks at room temperature, is best stored at -20 degree C. After reconstitution, short term (up to 1 week) store at 2 to 8 degree C. Long term, add 0.1% HSA or BSA, aliquot and store at -20 degree C.
other info1 :
Inactivation: Not applicable
other info2 :
Buffer: Not applicable. Preservative: No. Lyophilized: Yes
products categories :
Purified Cytokines and Growth Factors
products description :
Human Epidermal Growth Factor (EGF), Recombinant. Recombinant Human Epidermal Growth Factor is a single, non-glycosylated, polypeptide chain containing 53 amino acids and having a molecular weight of 6,222 Da. The sequence of the first five N-terminal a
ncbi mol weight :
6,222 Da
ncbi pathways :
Arf6 Signaling Events Pathway 138034!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!Ceramide Signaling Pathway 138023!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Delta-Notch Signaling Pathway 198879!!EGF Receptor (ErbB1) Signaling Pathway 137970!!EGFR Downregulation Pathway 106342!!EGFR Interacts With Phospholipase C-gamma Pathway 106338
ncbi summary :
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.