catalog number :
MBS319022
products type :
Recombinant Protein
products full name :
Human IGF-I, Recombinant
products short name :
Insulin Like Growth Factor I (IGF-I) Recombinant
other names :
insulin-like growth factor I; Insulin-like growth factor 1 (Somatomedin C), isoform CRA_c; insulin-like growth factor 1; MGF; IGF-IA; IGF-IB; somatomedin-C; OTTHUMP00000195080; OTTHUMP00000195081; OTTHUMP00000195082; OTTHUMP00000195083; OTTHUMP00000195084; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; insulin-like growth factor 1 (somatomedin C)
other gene names :
IGF1; IGF1; IGFI; IGF-I; IGF1A
uniprot entry name :
Q14620_HUMAN
specificity :
Insulin Like Growth Factor I (IGF-I) Recombinant
purity :
>98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE). Chromatographic techniques. Endotoxin level is less than 0.1ng/ug (IEU/ug). Product is sterile filtered.
form :
Purified, Lyophilized. Reconstitute using sterile deionized water to a concentration >100ug/ml. Further dilutions can be made in other aqueous buffers.
concentration :
1mg/ml (OD280nm, E0.1% = 0.502) (prior to lyophilization)
storage stability :
The lyophilized product, though stable for 3 weeks at room temperature, is best stored at -20 degree C. After reconstitution, short term (up to 1 week) store at 2 to 8 degree C. Long term, add 0.1% HSA or BSA, aliquot and store at -20 degree C.
other info1 :
Inactivation: Not applicable
other info2 :
Buffer: Lyophilized from 50mM acetic acid. Preservative: No. Lyophilized: Yes
products categories :
Purified Cytokines and Growth Factors
products description :
Human Insulin Like Growth Factor I (IGF-I), Recombinant. Recombinant Human IGF-1 is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular weight of 7,655Da. The sequence of the first five N-terminal amino acids w
ncbi acc num :
AAA52789.1
ncbi mol weight :
15,177 Da
ncbi pathways :
Adipogenesis Pathway (198832); Aldosterone-regulated Sodium Reabsorption Pathway (130626); Aldosterone-regulated Sodium Reabsorption Pathway (130590); Androgen Receptor Signaling Pathway (198806); Apoptosis Pathway (198797); Diabetes Pathways (105902); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285); Endochondral Ossification Pathway (198812); Focal Adhesion Pathway (198795)
ncbi summary :
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
uniprot summary :
Subcellular location: Secreted. By similarity RuleBase RU000406. Sequence similarities: Belongs to the insulin family. RuleBase RU000406