product summary
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company name :
MyBioSource
product type :
protein
product name :
EBV EBNA-1, Recombinant
catalog :
MBS318777
quantity :
1 mg
price :
1165 USD
more info or order :
product information
catalog number :
MBS318777
products type :
Antigen
products full name :
EBV EBNA-1, Recombinant
products short name :
Epstein-Barr Virus (EBV) Nuclear Antigen-1 (EBNA-1) Recombinant
products name syn :
Epstein-Barr Virus (EBV) Nuclear Antigen-1 (EBNA-1), Recombinant. Recombinant EBV (HHV-4) full-length EBNA-1. Contains a his-tag at the N-terminus. Molecular weight calculated from the amino acid sequence is 63 kDa.
other names :
EBNA-1 protein; Epstein-Barr nuclear antigen 1
other gene names :
EBNA1; EBNA-1
uniprot entry name :
EBNA1_EBVB9
host :
E Coli
sequence length :
641
specificity :
Epstein-Barr Virus (EBV) Nuclear Antigen-1 (EBNA-1) Recombinant
purity :
> 95% pure (SDS-PAGE).
form :
Purified, Liquid
concentration :
1.66 mg/ml(OD280nm, E^0.1% = 0.403)
storage stability :
Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
Suitable for use in ELISA (0.5 ug/mL) and Western blot.
other info1 :
Preservative: No Preservative
other info2 :
Buffer: 6 M Urea, 20 mM Phosphate, pH 8.0, 1 M Sodium Chloride, 0.1% Polyoxyethylene(10)Tridecylether.
products categories :
Infectious Disease Antigens and Toxins
ncbi gi num :
23893623
ncbi acc num :
CAD53427.1
uniprot acc num :
P03211
ncbi mol weight :
56,427 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival. Ref.8. Subunit structure: Interacts with human USP7. Interacts with human EBP2; this interaction is important for the stable segregation of EBV episomes during cell division but not for the replication of the episomes. Interacts with BGLF4; this interaction facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. Ref.4 Ref.5 Ref.6 Ref.8. Subcellular location: Host nucleus Ref.3. Sequence similarities: Belongs to the herpesviridae EBNA1 family.
size1 :
1 mg
price1 :
1165 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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