catalog number :
MBS318434
products full name :
CRP Free Serum
products short name :
C Reactive Protein (CRP) Free Serum
products name syn :
C Reactive Protein (CRP) Free Serum
other names :
C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; OTTHUMP00000033307; C-reactive protein, pentraxin-related
other gene names :
CRP; CRP; PTX1; MGC88244; MGC149895; PTX1
uniprot entry name :
CRP_HUMAN
host :
Pooled normal human serum
specificity :
C Reactive Protein (CRP) Free Serum
purity :
Immunoaffinity chromatography using anti-CRP monoclonal antibodies coupled to Sepharose CL4B
form :
Affinity purified, Liquid
storage stability :
Store at -20 degree C. Avoid multiple/freeze thaw cycles.
tested application :
EIA/ELISA
other info2 :
Buffer: Not applicable. Preservative: No. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infecti
products categories :
Purified Cardiac Markers
products description :
CRP free serum contains <0.02ng/ml of human CRP when tested by ELISA
ncbi mol weight :
25,039 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immunity Signaling Pathway (106387); Selenium Pathway (198825)
ncbi summary :
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq]
uniprot summary :
Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Cofactor: Binds 2 calcium ions per subunit. Subunit structure: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. Subcellular location: Secreted. Tissue specificity: Found in plasma. Induction: The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL1/interleukin-1 and IL6//interleukin-6. Miscellaneous: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium. Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain. Mass spectrometry: Molecular mass is 23028 Da from positions 19 - 224. Determined by MALDI. Ref.15Molecular mass is 22930 Da from positions 19 - 223. Determined by MALDI. Ref.15