catalog number :
MBS318420
products type :
Native Protein
products full name :
Apo AI/B Free Serum
products short name :
Apolipoprotein AI/B Free Serum
products name syn :
Apolipoprotein AI/B Free Serum
other names :
apolipoprotein A-I preproprotein; Apolipoprotein A-I; apolipoprotein A-I; apo-AI; apolipoprotein A1; apolipoprotein A-1; preproapolipoprotein A-I; apolipoprotein A-I; Apolipoprotein A1
other gene names :
Apoa1; Apoa1; apoA-I
uniprot entry name :
APOA1_RAT
host :
Pooled Defibrinated Human Serum
specificity :
Apolipoprotein AI/B Free Serum
purity :
Extraction of Apo AI and Apo B from normal human serum. The resulting serum is non-measurable for Apo AI and Apo B by TIA (Diasorin test kit). Product is 0.2um filtered
concentration :
Total protein: 4.4 g/dL (Biuret: Cobas-Mira)
storage stability :
Short term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.
other info1 :
Inactivation: Not applicable
other info2 :
Buffer: Not applicable. Preservative: 0.1% Sodium azide. Warnings: All human source materials have tested negative for HIV and HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious. This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
products categories :
Purified Lipoproteins
ncbi acc num :
NP_036870.1
ncbi gb acc num :
NM_012738.1
ncbi mol weight :
30,062 Da
ncbi pathways :
African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Fat Digestion And Absorption Pathway (194376); Fat Digestion And Absorption Pathway (194324); PPAR Signaling Pathway (83434); PPAR Signaling Pathway (450); Statin Pathway (198482); Vitamin Digestion And Absorption Pathway (199553); Vitamin Digestion And Absorption Pathway (199538)
ncbi summary :
major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase (LCAT) [RGD]
uniprot summary :
Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. Subunit structure: Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin. Subcellular location: Secreted. Tissue specificity: Major protein of plasma HDL, also found in chylomicrons. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A1/A4/E family.