protein

HSA (Low B12/Low Folate)

MBS318400

1 kg

5195 USD

Native Protein

HSA (Low B12/Low Folate)

Albumin, Human Serum (HSA) Low B12/Low Folate

Human Serum Albumin (HSA), Low B12 and Low Folate

albumin; Serum albumin; serum albumin; OTTHUMP00000160370; OTTHUMP00000196832; OTTHUMP00000220435; OTTHUMP00000220436; OTTHUMP00000220438; OTTHUMP00000220439; growth-inhibiting protein 20; cell growth inhibiting protein 42; albumin

ALB; ALB; PRO0883; PRO0903; PRO1341; DKFZp779N1935

ALBU_HUMAN

Phoresis Plasma

Albumin, Human Serum (HSA) Low B12/Low Folate

>99.3% pure (SPE gel electrophoresis). Cohn-Oncley Cold Alcohol Procedure

Purified, Lyophilized

Short term store at 2 to 8 degree C. Long term store at -20 degree C. Avoid multiple freeze/thaw cycles.

QC Information: B-12: 33.3pg/ml (SMAC). Folate: BDL ng/ml (SMAC). Biobuden (5%): <100 cfu/ml by Pour Plate at 30-35 degree C after 48 hours. Specific methodologies have not been tested using this product.

Inactivation: Not applicable

pH: 6.96 (5% solution at room temperature). Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: All human source materials have tested negative for HIV1, HIV2, HCV and HTLV-1 antibodies; HIV1, HIV2, HBV and HCV by NAT testing; HBsAg and HIV-1 Ag; and ALT (SGPT) by FDA approved tests. No test guarantees a product to be non-infectious. There

Purified Proteins and Bioactive Peptides

178344

P02768

69,367 Da

Bile Acid And Bile Salt Metabolism Pathway (106144); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Formation Of Platelet Plug Pathway (106029); HDL-mediated Lipid Transport Pathway (106158); Hemostasis Pathway (106028); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Of Lipids And Lipoproteins Pathway (160976); Platelet Activation Pathway (106034); Platelet Degranulation Pathway (106050)

Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq]

Function: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Ref.33. Subcellular location: Secreted. Tissue specificity: Plasma. Ref.35. Post-translational modification: Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracelllular medium.Acetylated on Lys-223 by acetylsalicylic acid. Polymorphism: A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. The sequence shown is that of variant albumin A. Involvement in disease: Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [. MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. Ref.64 Ref.65 Ref.66 Ref.67. Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains. Caution: A peptide arising from positions 166 to 174 was originally (Ref.23 and Ref.24) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulates fat digestion, lipid absorption, and blood flow. Sequence caution: The sequence AAF22034.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAF69644.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAG35503.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

1 kg

5195 USD