catalog number :
MBS318382
products type :
Native Protein
products full name :
FSH 98% Pure
products short name :
Follicle Stimulating Hormone (FSH) >98% Pure
products name syn :
Follicle Stimulating Hormone (FSH)
other names :
follicle-stimulating hormone; Follitropin subunit beta; follitropin subunit beta; FSH-B; FSH-beta; OTTHUMP00000232881; OTTHUMP00000232882; follitropin beta chain; follitropin, beta chain; follicle-stimulating hormone beta subunit; follicle stimulating hormone, beta polypeptide; Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain
other gene names :
FSHB; FSHB
uniprot entry name :
FSHB_HUMAN
host :
Human Pituitary Glands
specificity :
Follicle Stimulating Hormone (FSH) >98% Pure
form :
Purified, Lyophilized
concentration :
Activity: 6,351 IU/mg
storage stability :
Upon receipt, store at -20 degree C. Avoid multiple freeze-thaw cycles.
other info1 :
Inactivation: Not applicable
other info2 :
Contaminants: hTSH - 0.000027%. hLH - 0.000085 wt/wt. Buffer: Not applicable. Preservative: No. Lyophilized: Yes. Important Note: Centrifuge before opening to ensure complete recovery of vial contents. Warnings: All human source materials have tested non-reactive for HIV1, HIV2, HCV antibodies, HBsAg and STS by FDA approved methods. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be
products categories :
Purified Hormones and Steroids
ncbi mol weight :
14,700 Da
ncbi pathways :
Biosynthesis Of Amine And Peptide Hormones Pathway 366244!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (s) Signalling Events Pathway 119549!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Glycoprotein Hormones Pathway 160989!!GnRH Signaling Pathway 83091!!GnRH Signaling Pathway 502!!Hormone Ligand-binding Receptors Pathway 106369!!Metabolism Of Amino Acids And Derivatives Pathway 106169
ncbi summary :
The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]
uniprot summary :
Function: Stimulates development of follicle and spermatogenesis in the reproductive organs. Subunit structure: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular location: Secreted. Involvement in disease: Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD) [. MIM:229070]. Selective follicle-stimulating hormone deficiency is an uncommon cause of infertility, producing amenorrhea and hypogonadism in women and oligo or azoospermia with normal testosterone levels in normally virilised men. Ref.15 Ref.16 Ref.17. Pharmaceutical use: Available under the names Gonal-F or Metrodin HP (Serono) and Puregon (Organon). Used in the treatment of infertility in women with proven hypopituitarism or who have not responded to clomifene; or in superovulation treatment for assisted conception (such as in vitro fertilization). Metrodin HP is also used in the treatment of hypogonadotrophic hypogonadism in men for the stimulation of spermatogenesis. Sequence similarities: Belongs to the glycoprotein hormones subunit beta family.