catalog number :
MBS318318
products type :
Native Protein
products full name :
CEA Antigen Grade
products short name :
Carcinoembryonic Antigen (CEA) Antigen Grade
products name syn :
Carcinoembryonic Antigen (CEA) Antigen Grade
other names :
carcinoembryonic antigen; Carcinoembryonic antigen; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
other gene names :
CEACAM6; CEA; NCA; CEAL; CD66c; CEACAM6
uniprot entry name :
Q13985_HUMAN
host :
Human Metastatic Liver
specificity :
Carcinoembryonic Antigen (CEA) Antigen Grade
purity :
Immunoaffinity purification. SDS-PAGE denaturing: multiple protein bands 150-210kDa
form :
Affinity Purified, Liquid
concentration :
4.50 mg/ml
storage stability :
Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.
tested application :
EIA/ELISA
app notes :
Suitable as an immunogen for antisera production, tracer for iodination and stadard for immunoassay.
other info1 :
Inactivation: Not applicable
other info2 :
Buffer: 0.1M PBS, pH 7.4 containing 2% Methyl-mannoside. Preservative: 0.2% Sodium azide. Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains. A blood sample from the tissue donor tested negative for HIV 1, HIV 2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
products categories :
Purified Reagents for Cancer Research
ncbi acc num :
AAA51971.1
ncbi mol weight :
15,545 Da
ncbi summary :
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
uniprot summary :
CEACAM6: Belongs to the immunoglobulin superfamily. CEA family. Protein type: Membrane protein, GPI anchor; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: protein binding. Biological Process: cell-cell signaling; signal transduction; blood coagulation; leukocyte migration