catalog number :
MBS318223
products type :
Native Protein
products full name :
Apo AI/B Calibrator 3
products short name :
Apolipoprotein AI/B (Apo AI/B) Calibrator 3
products name syn :
Apolipoprotein AI/B Calibrator 3
other names :
apolipoprotein A-I preproprotein; Apolipoprotein A-I; apolipoprotein A-I; apo-AI; apolipoprotein A1; apolipoprotein A-1; preproapolipoprotein A-I; apolipoprotein A-I; Apolipoprotein A1
other gene names :
Apoa1; Apoa1; apoA-I
uniprot entry name :
APOA1_RAT
host :
Defibrinated Human Plasma
specificity :
Apolipoprotein AI/B (Apo AI/B) Calibrator 3
purity :
Multi-step precipitation. Product is 0.2um filtered.
concentration :
Total protein: 3.1g/dL (Biuret: Cobas-Mira). Apo AI: 312mg/dL. Apo B: 312mg/dL (Turbidimetric Assay (Cobas-Mira)
storage stability :
Short term, store at 2 to 8 degree C. Long term, store at -20 degree C. Avoid multiple freeze/thaw cycles.
other info1 :
Inactivation: Not applicable.
other info2 :
Buffer: 0.1M Sodium borate, 0.2M Sodium chloride containing proprietary stabilizers. Preservative: 0.1% Sodium azide. Warnings: All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infecti
products categories :
Purified Lipoproteins
ncbi acc num :
NP_036870.1
ncbi gb acc num :
NM_012738.1
ncbi mol weight :
30,062 Da
ncbi pathways :
African Trypanosomiasis Pathway (194377); African Trypanosomiasis Pathway (194323); Fat Digestion And Absorption Pathway (194376); Fat Digestion And Absorption Pathway (194324); PPAR Signaling Pathway (83434); PPAR Signaling Pathway (450); Statin Pathway (198482); Vitamin Digestion And Absorption Pathway (199553); Vitamin Digestion And Absorption Pathway (199538)
ncbi summary :
major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase (LCAT) [RGD]
uniprot summary :
Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. Subunit structure: Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin. Subcellular location: Secreted. Tissue specificity: Major protein of plasma HDL, also found in chylomicrons. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A1/A4/E family.