protein

Vitamin D Bind.Prot (GC-Glob.)

MBS318215

1 mg

225 USD

Native Protein

Vitamin D Bind.Prot (GC-Glob.)

Vitamin D Binding Protein (Gc-Globulin)

Purified Vitamin D Binding Protein (GC Globulin)

vitamin D-binding protein isoform 1; Vitamin D-binding protein; vitamin D-binding protein; VDB; gc-globulin; OTTHUMP00000160364; OTTHUMP00000218973; OTTHUMP00000218974; OTTHUMP00000218975; vitamin D-binding alpha-globulin; group-specific component (vitamin D binding protein); Gc-globulin; Group-specific component

GC; GC; DBP; GRD3; VDBG; VDBP; DBP/GC

VTDB_HUMAN

Human Plasma

474

Vitamin D Binding Protein (Gc-Globulin)

>95% pure (SDS-PAGE)

Purified, Lyophilized. Reconstitute with distilled water.

3.76 mg/ml (prior to lyophilization)

Store lyophilized product at -20 degree C to -70 degree C. After reconstitution, aliquot and store at -20 degree C to -70 degree C. Avoid multiple freeze/thaw cycles.

Specific methodologies have not been tested using this product.

Inactivation: Not applicable

Molecular Weight: 52 kDa (SDS-PAGE, reducing conditions). Buffer: Lyophilized from 20mM Sodium Phosphate, pH 7.4 containing 150mM Sodium chloride. Preservative: No. Lyophilized: Yes. Warnings: All human source materials have tested negative for HIV 1 and HIV 2 and non-reactive for HBsAg, anti-HCV and anti-HBc by FDA required tests. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Purified Proteins and Bioactive Peptides

Vitamin D Bind.Prot (GC-Glob.); Purified Vitamin D Binding Protein (GC Globulin). Molecular weight 52kDa (SDS-PAGE, reducing conditions)

32483410

NP_000574.2

NM_000583.3

P02774

52 kDa

Metabolism Of Lipids And Lipoproteins Pathway (160976); Metabolism Of Steroid Hormones And Vitamins A And D Pathway (106150); Metabolism Of Vitamins And Cofactors Pathway (106249); Vitamin D (calciferol) Metabolism Pathway (160956)

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Function: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Subcellular location: Secreted. Polymorphism: Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele. Sequence similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains. Sequence caution: The sequence BAG60654.1 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.

1 mg

225 USD