protein

Human Apolipoprotein AII (Apo-AII)

MBS318206

0.5 mg

230 USD

Native Protein

Human Apolipoprotein AII (Apo-AII)

Apolipoprotein AII (Apo AII)

Apolipoprotein A-II; Apolipoprotein A-II; apolipoprotein A-II; apolipoprotein A2; OTTHUMP00000032244; apolipoprotein A-II; Apolipoprotein A2

APOA2; APOA2; apoAII; Apo-AII; ApoA-II

APOA2_HUMAN

Human Plasma, High Density Lipoprotein

100

Apolipoprotein AII (Apo AII)

>95% pure (SDS-PAGE). Single band on polyacrylamide electrophoresis

Purified, Liquid

1.63 mg/ml

Store at = 1mg/ml as precipitation may occur below 1mg/ml. Avoid multiple freeze/thaw cycles. Shipping: ships on Dry Ice

Specific methodologies have not been tested using this product

Note: Centrifuge before opening to ensure complete recovery of vial contents. Inactivation: Not applicable

Buffer: 10mM Ammonium Bicarbonate, pH 7.4. Preservative: No. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Warnings: All human source materials have tested negative for anti-HIV 1 and anti-HIV 2, and non-reactive for anti-HCV and anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.

Purified Lipoproteins

Human Apolipoprotein AII (Apo-AII)

Malik, Gunjan., et al., (2005), "Serum Levels of an Isoform of Apolipoprotein AII as a Potential Marker for Prostate Cancer", Clinical Cancer Research, 11, 1073-1085

114000

P02652.1

P02652

11,175 Da

Chylomicron-mediated Lipid Transport Pathway (106157); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Lipid Digestion, Mobilization, And Transport Pathway (106111); Lipoprotein Metabolism Pathway (106156); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); Statin Pathway (198852)

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq]

Function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Subunit structure: Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP. Ref.14 Ref.15 Ref.18. Subcellular location: Secreted. Tissue specificity: Plasma; synthesized in the liver and intestine. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Sequence similarities: Belongs to the apolipoprotein A2 family. Mass spectrometry: Molecular mass is 8701.2 Da from positions 24 - 100. Determined by MALDI. Ref.16Molecular mass is 8823.4 Da from positions 24 - 100. Determined by MALDI. Cysteinylated ApoA-II. Ref.16Molecular mass is 17421.3 Da from positions 24 - 100. Determined by MALDI. Homodimer. Ref.16Molecular mass is 17293.4 Da from positions 24 - 100. Determined by MALDI. Heterodimer with apolipoprotein A-II(1-76). Ref.16Molecular mass is 8578.3 Da from positions 24 - 99. Determined by MALDI. Ref.16Molecular mass is 17166.2 Da from positions 24 - 99. Determined by MALDI. Homodimer. Ref.16

0.5 mg

230 USD