catalog number :
MBS318180
products type :
Native Protein
products full name :
Human Cathepsin B
products short name :
Cathepsin B
other names :
cathepsin B; Cathepsin B; cathepsin B; BCSB; BCSB
other gene names :
CTSB; CTSB; CTSB
uniprot entry name :
CATB_BOVIN
specificity :
Cathepsin B
purity :
>95% pure (SDS-PAGE)
concentration :
Total protein: 0.37mg/ml. Specific Activity: 385 Units/mg protein using Z-Arg-Arg-beta-NA as a substrate. One unit is defined as the amount of enzyme that hydrolyzes one umole of 2-naphtylamine per minute at 40 degree C, pH 6.0, in the presence of DTT>
storage stability :
Store at -80 degree C.
other info1 :
Inactivation: Not applicable.
other info2 :
Buffer: 50mM Sodium acetate, pH 5.0, with 1mM EDTA. Preservative: No. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
products categories :
Purified Enzymes
products description :
Prepared from liver tissue that was shown to be nonreactive for HBsAg, anti-HCV, anti HBc, and negative for anti-HIV 1 & 2 by FDA required tests
ncbi acc num :
NP_776456.1
ncbi gb acc num :
NM_174031.2
ncbi mol weight :
36,661 Da
ncbi pathways :
Antigen Processing And Presentation Pathway (84313); Antigen Processing And Presentation Pathway (485); Lysosome Pathway (98762); Lysosome Pathway (96865)
uniprot summary :
Function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Catalytic activity: Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg- -Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. Subunit structure: Interacts with SRPX2. By similarity. Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Subcellular location: Lysosome. Melanosome. Sequence similarities: Belongs to the peptidase C1 family.