protein

Human Plasma Transferrin

MBS318178

100 mg

200 USD

Native Protein

Human Plasma Transferrin

Transferrin

Human Transferrin (Holo Transferrin)

serotransferrin; Serotransferrin; serotransferrin; siderophilin; OTTHUMP00000197155; beta-1 metal-binding globulin; transferrin; Beta-1 metal-binding globulin; Siderophilin

TF; TF; PRO1557; PRO2086; DKFZp781D0156

TRFE_HUMAN

Human Plasma

698

Transferrin

>95% pure (SDS PAGE)

Purified, Lyophilized. Reconstitute with 1.31ml distilled water.

76.3mg/ml (prior to lyophilization) (Biuret)

Upon receipt, store at -20 degree C. Avoid multiple freeze/thaw cycles.

Iron content: >1.0ug/mg protein . Total Iron Binding Capacity: 1.2-1.6ug/mg

Inactivation: Not applicable.

Buffer: Lyophilized from 20mM Phosphate buffer, 150mM Sodium chloride, pH 7.4. Preservative: No. Lyophilized: Yes. Warnings: All human source materials have tested negative for HIV 1 and HIV 2 antibodies and non-reactive for HCV and HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues

Purified Proteins and Bioactive Peptides

4557871

NP_001054.1

NM_001063.3

P02787

77,064 Da

EPHB Forward Signaling Pathway (138047); Formation Of Platelet Plug Pathway (106029); HIF-1-alpha Transcription Factor Network Pathway (138045); Hemostasis Pathway (106028); Iron Uptake And Transport Pathway (187191); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Platelet Activation Pathway (106034); Platelet Degranulation Pathway (106050); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq]

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Subunit structure: Monomer. Subcellular location: Secreted. Tissue specificity: Expressed by the liver and secreted in plasma. Polymorphism: Different polymorphic variants of transferrin are known. The sequence shown is the predominant electrophoretic variant (C1 or TF*C1). Involvement in disease: Defects in TF are the cause of atransferrinemia (ATRAF) [. MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Ref.4 Ref.39. Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains. Sequence caution: The sequence AAF22007.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

100 mg

200 USD