protein

Purif. Alpha 2 HS Glycoprot

MBS318171

1 mg

225 USD

Native Protein

Purif. Alpha 2 HS Glycoprot

Alpha 2 HS Glycoprotein

Purified Alpha 2 HS Glycoprotein

alpha-2-HS-glycoprotein; Alpha-2-HS-glycoprotein; alpha-2-HS-glycoprotein; fetuin-A; OTTHUMP00000210158; OTTHUMP00000210159; alpha-2-Z-globulin; ba-alpha-2-glycoprotein; alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A

AHSG; AHSG; AHS; A2HS; HSGA; FETUA; FETUA

FETUA_HUMAN

Human Plasma

367

Alpha 2 HS Glycoprotein

>90% pure (SDS-PAGE)

Purified, Lyophilized. Reconstitute with 335.6ul deionized water.

2.98mg/ml (prior to lyophilization)

Store at -20 degree C. Avoid multiple freeze/thaw cycles.

Inactivation: Not applicable.

Buffer: Lyophilized from 20mM Tris-HCl, pH 8.0, containing 200mM Sodium chloride. Preservative: No. Lyophilized: Yes. Warnings: All human source materials have tested negative for HIV 1, HIV 2, HCV, and HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or

Purified Proteins and Bioactive Peptides

156523970

NP_001613.2

NM_001622.2

P02765

39,325 Da

BMP Receptor Signaling Pathway (137948)

Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq]

Function: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Subunit structure: Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Subcellular location: Secreted. Tissue specificity: Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Ref.26. Post-translational modification: Phosphorylation sites are present in the extracelllular medium. Polymorphism: There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256. Sequence similarities: Belongs to the fetuin family.Contains 2 cystatin fetuin-A-type domains.

1 mg

225 USD