protein

Human Beta-2 gp I, Apo H

MBS318124

1 mg

830 USD

Native Protein

Human Beta-2 gp I, Apo H

Beta-2 Glycoprotein I, Apolipoprotein H (Apo H)

Beta 2 Glycoprotein I, Apolipoprotein H

Beta-2-glycoprotein 1; Beta-2-glycoprotein 1; beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein; apolipoprotein H (beta-2-glycoprotein I); APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I

APOH; APOH; BG; B2G1; B2GP1; B2G1

APOH_HUMAN

Human plasma

Beta-2 Glycoprotein I, Apolipoprotein H (Apo H)

>95% pure (SDS-PAGE). Column chromatography

Purified, Liquid

1.421 mg/ml (BCA)

Upon receipt, store at -20 degree C or -70 degree C. Avoid multiple freeze/thaw cycles. Shipping: Ships with Dry Ice

EIA/ELISA

After thawing, mix thoroughly by vortexing before use. Suitable for use in ELISA (0.2-0.4ug/well). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Inactivation: Not applicable

Buffer: 20mM HEPES-NaOH, 0.16M Sodium chloride, pH 7.5 with 0.1mM PMSF, 20% glycerol. Preservative: Proprietary formula containing 0.1% preservative, bromo-nitro-dioxane/methylisothiazoline. Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Warnings: All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infection. Important Note: Centrifuge before opening to ensure recovery of vial contents.

Purified Autoimmune Reagents

Human Beta-2 gp I, Apo H. Beta 2 Glycoprotein I, Apolipoprotein H

543826

P02749

38,298 Da

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq]

Function: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. Subcellular location: Secreted. Tissue specificity: Expressed by the liver and secreted in plasma. Post-translational modification: N- and O-glycosylated. Ref.10 also reports glycosylation on 'Asn-188' for their allele. Ref.10 Ref.15 Ref.16 Ref.17 Ref.18 Ref.19 Ref.20 Ref.21. Sequence similarities: Contains 4 Sushi (CCP/SCR) domains.

1 mg

830 USD